The saccule-to-utricle ratio inversion may serve as an effective imaging marker for diagnosis of early-stage Meniere disease, according to a study published online July 27 in The Laryngoscope.
Wenting Deng, M.D., from Sun Yat-Sen Memorial Hospital at Sun Yat-Sen University in Guangzhou, China, and colleagues compared the saccule-to-utricle ratio inversion in patients with early-stage (56 patients) versus late-stage (70 patients) Meniere disease based on magnetic resonance imaging.
The researchers found that 46.43 percent of the early-stage group showed an enlarged saccule that was larger than the utricle, with saccule-to-utricle ratio inversion. In the late-stage Meniere disease group, only four individuals (5.71 percent) showed saccule-to-utricle ratio inversion. Within the early-stage Meniere disease subgroup, those with a disease duration of no more than six months had a higher proportion of saccule-to-utricle ratio inversion than the subgroup with a disease duration of more than six months (70 versus 33.33 percent).
“Saccule-to-utricle ratio inversion may serve as an effective imaging marker for diagnosis of early-stage Meniere disease,” the authors write. “Our finding suggests that endolymphatic hydrops in Meniere disease may primarily originate from the saccule.”
More information:
Wenting Deng et al, Comparing the Saccule‐to‐Utricle Ratio in Early‐ Versus Late‐Stage Meniere’s Disease Patients, The Laryngoscope (2024). DOI: 10.1002/lary.31655
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Saccule-to-utricle ratio inversion may ID early-stage Meniere disease (2024, September 3)
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