ScienceElectrical zaps can 'reawaken' lost neural connections, helping paralyzed...

Electrical zaps can ‘reawaken’ lost neural connections, helping paralyzed people walk again


People with paralyzing spinal cord injuries can walk again with the help of medical devices that zap their nerves with electricity. But the designers of these new implants weren’t completely sure of how they restored motor function over time — now, a new study provides clues. 

The new study of humans and lab mice, published Nov. 9 in the journal Nature (opens in new tab), pinpoints a specific population of nerve cells that seems key to recovering the ability to walk after a paralyzing spinal cord injury. With a jolt of electricity, an implant can switch these neurons on and thus jumpstart a cascade of events in which the very architecture of the nervous system changes. This cellular remodel restores the lost lines of communication between the brain and the muscles needed for walking, allowing once-paralyzed people to walk again, the researchers concluded.



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